1. CRION is rare in children is steroid dependent optic neuritis, relapse off steroids
2. One presenter stated that ON + TM presentation "Devics presentation" has been MOG in "all cases she has seen"
3. Pediatric NMO has more brain lesions
4. 4 MOG phenotypes in kids: a. Recurrent ADEM b. recurrent ON c. ADEM followed by ON d. NMOSD with MOG positive serology rather than Aquaphorin 4 positive
5. No cases of simultaneous MOG positive and MS
6. MOG has female predominance 1.5:1 and mean age of onset of 21
7. MOG respods best to IVIG not Rituxan; has 20 % rate of relapses but they are bad relapses.
Source 2017 Consortium session on pediatric MS
2. One presenter stated that ON + TM presentation "Devics presentation" has been MOG in "all cases she has seen"
3. Pediatric NMO has more brain lesions
4. 4 MOG phenotypes in kids: a. Recurrent ADEM b. recurrent ON c. ADEM followed by ON d. NMOSD with MOG positive serology rather than Aquaphorin 4 positive
5. No cases of simultaneous MOG positive and MS
6. MOG has female predominance 1.5:1 and mean age of onset of 21
7. MOG respods best to IVIG not Rituxan; has 20 % rate of relapses but they are bad relapses.
Source 2017 Consortium session on pediatric MS
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